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RPL26/uL24 UFMylation is essential for ribosome-associated quality control at the endoplasmic reticulum.

Scavone F, Gumbin SC, Da Rosa PA, Kopito RR.Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2220340120. doi: 10.1073/pnas.2220340120.

A non-canonical scaffold-type E3 ligase complex mediates protein UFMylation.

Peter JJ, Magnussen HM, DaRosa PA, Millrine D, Matthews SP, Lamoliatte F, Sundaramoorthy R, Kopito RR, Kulathu Y.EMBO J. 2022 Nov 2;41(21):e111015. doi: 10.15252/embj.2022111015

PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion.

Lyschik S, Lauer AA, Roth T, Janitschke D, Hollander M, Will T, Hartmann T, Kopito RR, Helms V, Grimm MOW, Schrul B.Front Cell Dev Biol. 2022 Apr 26;10:859052. doi: 10.3389/fcell.2022.859052.

Ribosomal protein RPL26 is the principal target of UFMylation.

Walczak CP, Leto DE, Zhang L, Riepe C, Muller RY, DaRosa PA, Ingolia NT, Elias JE, Kopito RR.Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1299-1308. doi: 10.1073/pnas.1816202116.

Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.

Leto DE, Morgens DW, Zhang L, Walczak CP, Elias JE, Bassik MC, Kopito RR.Mol Cell. 2019 Jan 17;73(2):377-389.e11. doi: 10.1016/j.molcel.2018.11.015

Proteomic analysis of monolayer-integrated proteins on lipid droplets identifies amphipathic interfacial α-helical membrane anchors.

Pataki CI, Rodrigues J, Zhang L, Qian J, Efron B, Hastie T, Elias JE, Levitt M, Kopito RR.Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8172-E8180. doi: 10.1073/pnas.1807981115. 

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